Somatostatin Receptors

Cell surface proteins that bind somatostatin and trigger intracellular changes which influence the behavior of cells. Somatostatin is a hypothalamic hormone, a pancreatic hormone, and a central and peripheral neurotransmitter. Activated somatostatin receptors on pituitary cells inhibit the release of growth hormone; those on endocrine and gastrointestinal cells regulate the absorption and utilization of nutrients; and those on neurons mediate somatostatin's role as a neurotransmitter.

Also Known As:

Somatostatin Receptor; Receptors, Somatostatin; Receptors, SRIH; SRIH Receptors; Receptor, Somatostatin; Receptors, Somatotropin Release Inhibiting Hormone

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Membrane Proteins: 10262
    - Cell Surface Receptors: 2156
      - G-Protein-Coupled Receptors: 4858
        Somatostatin Receptors: 3332
      - Peptide Receptors: 1208
        Neuropeptide Receptors: 97
        Somatostatin Receptors: 3332
        Pituitary Hormone-Regulating Hormone Receptors: 1
        Somatostatin Receptors: 3332
        Pancreatic Hormone Receptors
        Somatostatin Receptors: 3332
      - Neurotransmitter Receptors: 577
        Neuropeptide Receptors: 97
        Somatostatin Receptors: 3332

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Disease

Drug/Important Bio-Agent (IBA)